北京百奥莱博主要从事生物试剂的生产和销售,产品线涵盖北京现货FRAP/mTOR抑制剂(Rapamycin)(国产,进口)在内的细胞生物学试剂产品,还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。
名称:北京现货FRAP/mTORYZ剂(Rapamycin)(国产,进口)
英文名:AY 22989
规格:1mg
编号:YT347
CAS:53123-88-9
产地:国产|进口
品Pai:百奥莱博
本品可与FKBP12形成复合物,随后结合并YZFRAP/mTOR。mTOR 是哺乳动物中rapamycin的作用靶点,也被称为FRAP或FAFT,是一个Ser/Thr蛋白激酶,可以激活p70 S6 kinase。Rapamycin对于p70 S6 kinase的YZ作用的IC50为0.05nM。Rapamycin通过YZFRAP/mTOR可以YZp70 S6 kinase的磷酸化和激活,YZ4E-BP1/PHAS1的磷酸化并促进其对eIF4E的结合和YZ。
CAS:53123-88-9
分子式:C51H79NO13
分子量:914.17
纯度:>98%。
注意事项:
1. 本产品对人体有害,操作时请小心,并注意有效防护以避免直接接触人体或吸入体内。
2. 本Rapamycin在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
储存条件:-20℃避光,有效期6个月。
更多有关北京现货FRAP/mTORYZ剂(Rapamycin)(国产,进口)的价格及使用说明等,请联系我们的业务经理王欣女士咨询,我公司还销售以下产品:
·兔抗OOEP抗体
编号:YT748
英文名称:OOEP Rabbit Polyclonal Antibody
规格:50μl
本品为来源于兔的抗OOEP的多克隆抗体。
宿主:兔
克隆性:多克隆抗体
交叉反应性:小鼠
用途:IHC
推荐稀释比例:IHC(1:200)
About this Antibody | |
Name | OOEP Rabbit Polyclonal Antibody |
Category | Polyclonal antibody(pAb); Primary antibody |
Isotype | IgG |
Purification | Peptide affinity purified |
About the Immunogen | |
Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to mouse Ooep. |
Gene ID | 441161 |
SwissProt | A6NGQ2 |
Synonyms | KHDC2; FLOPED; HOEP19; C6orf156 |
Category | Chromatin Regulation / Nuclear Function |
Background | OOEP (oocyte-expressed protein homolog), also known as KHDC2 (KH homology domain-containing protein 2) or OEP19 (oocyte- and embryo-specific protein 19), is a 149 amino acid cytoplasmic protein that belongs to the KHDC1 family and contains one KH domain. As a member of the subcortical maternal complex (SCMC), OOEP is necessary for zygotes to progress nd the first embryonic cell divisions. In addition to OOEP, the SCMC includes NALP5 and TLE6. The gene that encodes OOEP consists of approximately 26,579 bases and maps to human chromosome 6q13. With 170 million base pairs, chromosome 6 comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. |
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