A0561 PTEN (Phospho-Ser385) Antibody_详细资料

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A0561   PTEN （Phospho-Ser385） Antibody

Reactivity Applications MW. Source

H, M IHC ELISA 47 kDa Rabbit

Note: The product is for research use only, not for use in diagnostic or therapeutic procedures.

Product Name PTEN （Phospho-Ser385） Antibody

Synonyms MMAC1; Mutated in multiple advanced cancers 1; phosphatase ａnd tensin homolog gene; Protein-tyrosine phosphatase PTEN; TEP1

Immunogen The antiserum was produced against synthesized peptide derived from human PTEN around the phosphorylation site of Ser385.

Immunogen Region C-terminal

Clonality Polyclonal

Modification sites H:S385 M:S385

Application dilutions IHC: 1:50~1:100 ELISA: 1:1000

Specificity PTEN （Phospho-Ser385） Antibody detects endogenous levels of PTEN only when phosphorylated at serine385.

Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.

Physical Form Rabbit IgG in phosphate buffered saline （without Mg2+ ａnd Ca2+）, pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.

Concentration 1 mg/ml

Storage/Stability Store at -20℃/1 year

NCBI Gene Symbol PTEN

Database Links

Gene ID: 5728 Swiss-Prot #: P60484

OMIM #: 137800 / 153480 / 158350 / 176807 / 176920 / 275355 / 276950 / 601728 / 605309 / 608089 / 612242 Unigene #: Hs.500466

Application images
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using PTEN （Phospho-Ser385） Antibody. The picture on the right is treated with the synthesized peptide.

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Product Name	PTEN （Phospho-Ser385） Antibody
Synonyms	MMAC1; Mutated in multiple advanced cancers 1; phosphatase ａnd tensin homolog gene; Protein-tyrosine phosphatase PTEN; TEP1
Immunogen	The antiserum was produced against synthesized peptide derived from human PTEN around the phosphorylation site of Ser385.
Immunogen Region	C-terminal
Clonality	Polyclonal
Modification sites	H:S385 M:S385
Application dilutions	IHC: 1:50~1:100 ELISA: 1:1000
Specificity	PTEN （Phospho-Ser385） Antibody detects endogenous levels of PTEN only when phosphorylated at serine385.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.
Physical Form	Rabbit IgG in phosphate buffered saline （without Mg2+ ａnd Ca2+）, pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.
Concentration	1 mg/ml
Storage/Stability	Store at -20℃/1 year