产品介绍:
BTA-1是一种荧光性硫代黄素-T衍生物,它与淀粉状蛋白沉积物具有很高的亲和力(Ki = 11 nM for Ab 40)。BTA-1可穿过血脑屏障,并且其显现的亲和力比硫代黄素T高50倍。它可以用来选择性地对转基因鼠PS1/APP大脑的脑斑和脑血管沉积物进行染色。
英文注释:
BTA-1 is a fluorescent Thioflavin-T derivative that exhibits high affinity for amyloid deposits (Ki = 11 nM for Ab 40). It crosses the blood brain barrier and displays up to 50-fold higher affinity than Thioflavin-T, and used for selectively staining cerebral plaques and cerebrovascular amyloid deposits in the brains of PS1/APP transgenic mice.
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