Murine TRAIL/重组小鼠TRAIL
产品编号：M10-128
产品规格：50μg
Description: TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain", which activates the cell’s apoptotic machinery. Recombinant murine soluble TRAIL is a 174 amino acid polypeptide (20.0 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein.
Source: E. coli
Molecular Weight: 20.0 kDa
Purity: > 95% by SDS-PAGE
Endotoxin level/内毒素水平: < 0.1 ng per μg of TRAIL
Stabilizer: none
Formulation: lyophilized
Biological Activity: Determined by the dose-dependent stimulation of MIP-2 production by mouse spleen cells using a concentration range of 10-100 ng/ml.
Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted TRAIL is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C.
Avoid repeated freeze-thaw cycles.
Usage: Murine TRAIL offered for research use. Not for drug use. Not for human use.
