上皮钠离子通道蛋白γ抗体Anti-ENaCg的产品说明（为您现货供应，详询）：
--产品介绍：Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel （Deg/ENaC） superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC （alpha, beta, and gamma） protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator （CFTR） chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension （Liddel’s syndrome） and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism （PHA-1）.Subcellular Location : "Apical cell membrane; Multi-pass membraneSimilarity : Belongs to the amiloride-sensitive sodium channel （TC 1.A.6） family. SCNN1G subfamily.Subunit : Probable heterotrimer containing one alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2.
--该抗体来源于：（Rabbit）
--上皮钠离子通道蛋白γ抗体的参数介绍：
1、浓度：1mg/1ml
2、交叉反应：hu, mo, rat, dog, Rb
3、产品类型：一抗
4、研究领域：肿瘤免疫学神经生物学信号转导通道蛋白细胞膜受体
5、蛋白分子量：predicted molecular weight: 71kDa
6、性状：Lyophilized or Liquid
7、免疫原：KLH conjugated synthetic peptide derived from human ENaCg
8、亚型：polyclonal
9、纯化方法：affinity purified by Protein A
10、储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
11、产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
12、保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
（1mg/1ml上皮钠离子通道蛋白γ抗体Anti-ENaCg，的相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）
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