CD163抗体 Anti-CD163/M130

CD163抗体Anti-CD163/M130的产品说明（为您现货供应，详询）：
--产品介绍：CD163 is a 130 kDa membrane glycoprotein. It is a member of the scavenger receptor cysteine-rich superfamily and is a receptor for the hemoglobin-haptoglobin complex. CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation. CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes. CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone. Lipopolysaccharide （LPS） and phorbol myristate acetate （PMA） both induce shedding of CD163 from the cell surface into plasma or cell supernatant.CD163是SRCR超家族成员之一，又称为血红蛋白清道夫受体（hemoglobin scavenger receptor, HbSR）、M130或p155。CD163的表达水平受很多因素调节，糖皮质激素及KY介质如IL-10以及IL-6能上调CD163, 而促炎介质如脂多糖（lipopolysaccharide, LPS）、γ-干扰素（interferon-γ， IFN-γ）以及TNF-α则YZCD163表达。 CD163是一种I型膜蛋白，又称为M130抗原、Ber-Mac3、Ki-M8或SM4。CD163限制性表达于单核/巨噬细胞系，所有循环系统的单核细胞和大多数组织（除外淋巴滤泡套区和SFZX）的巨噬细胞均阳性表达，主要用于单核/巨噬细胞的检测。
--该抗体来源于：（Rabbit）
--CD163抗体的参数介绍：
1、浓度：1mg/1ml
2、交叉反应：hu, mo, rat, pig, cow, hrs, dog
3、产品类型：一抗
4、研究领域：心血管免疫学细胞膜受体细胞类型标志物
5、蛋白分子量：predicted molecular weight: 130kDa
6、性状：Lyophilized or Liquid
7、免疫原：KLH conjugated synthetic peptide derived from human CD163
8、亚型：polyclonal
9、纯化方法：affinity purified by Protein A
10、储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
11、产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
12、保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

（1mg/1mlCD163抗体Anti-CD163/M130，的相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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