Nigericin sodium/尼日利亚菌素钠
产品编号:N015
产品规格:10mg/50mg
CAS Number | 28380-24-7 |
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Molecular Formula | C40H67NaO11 |
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Molecular Weight | 746.94 g/mol |
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Form | Powder |
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Appearance | White to off-white powder |
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Purity Level | ≥99.0% |
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Solubility | Chloroform: 10 mg/mL
Methanol: 10 mg/mL
Ethanol: 5 mg/mL
Water: Practically insoluble |
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Source | Streptomyces Hygroscopicus |
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Boiling Point | 779.9 °C |
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Flash Point | 227.9 °C |
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Storage Conditions | 2-8 °C |
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Description
Nigericin sodium is an antibiotic ionophore produced by Streptomyces hygroscopicus. Nigericin is insoluble in water but soluble in methanol and chloroform (10 mg/mL).
Mechanism
Nigericin sodium acts as an antiporter of H and K ions by exchanging K for H. This ionic imbalance rapidly decreases the intracellular pH.
Cancer Applications