Griseofulvin/灰黄霉素
产品编号:G008
产品规格:25g/50g
CAS Number | 126-07-8 |
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Molecular Formula | C17H17ClO6 |
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Molecular Weight | 352.77 g/mol |
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Form | Powder |
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Appearance | White powder |
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Purity Level | ≥90.0% |
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Solubility | Water: Practically insoluble |
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Source | Penicillium Griseofulvum |
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Water Content (Karl Fisher) | Loss on drying: <1.0% |
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Boiling Point | 570.4 °C |
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Melting Point | 217-224 °C |
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Flash Point | 228 °C |
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Storage Conditions | -20 °C |
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Description
Griseofulvin is an insoluble (0.00864 mg/mL) fungistatic antifungal.
Mechanism
The mechanism of action is not well described, but is currently thought to bind to tubulin and interfere with mitosis. In addition, griseofulvin is thought to inhibit synthesis of nucleic acids.
Spectrum
Griseofulvin targets fungi responsible for tinea infections including Microsporum, Epidermophyton, and Trichophytonspecies.
Microbiology Applications
Griseofulvin is commonly used in clinical in vitro micro