BIA-G1212 Griseofulvin/灰黄霉素

Griseofulvin/灰黄霉素
产品编号：BIA-G1212 
产品规格：25mg/100mg 
Griseofulvin   CAS Number. 126-07-8
  alternate Name(s):  Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533  
Griseofulvin is a spiro benzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect to the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.灰黄霉素           CAS 号. 126-07-8
别名：Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533
灰黄霉素是由一些青霉菌产生的螺旋苯并呋喃，于20世纪30年代由Raistrick研究小组首次分离。灰黄霉素是一种选择性的抗真菌剂用于ZL动物和人类的皮肤感染。灰黄霉素通过结合真菌的微管蛋白和YZ有丝分裂纺锤体的形成发挥作用。灰黄霉素结合角蛋白的能力被认为是它作用于皮肤寄生真菌的一个重要的方面。近来，灰黄霉素成为青霉属分类学中的一个重要的表型标志物。