货号：
BS-ab00024
抗体名：
anti-AASDHPPT-antibody
抗体英文名：
anti-AASDHPPT-antibody
靶点：
BHLHE78, MOP1, PASD8
浓度：
1mg/ml
应用范围：
ELISA,IHC,IF,FC,WB
宿主：
Rabbit
供应商：
BOSGENE
数量：
99
级别：
none
目录编号：
none
抗原来源：
Recombinant protein
保质期：
一年
适应物种：
Human,Mouse ,Rat
标记物：
None
克隆性：
单克隆
保存条件：
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
形态：
liquid
亚型：
IgG
免疫原：
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
规格：
100μg
Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Activation requires recruitment of transcriptional coactivators such as CREBPB and EP300. Activity is enhanced by interaction with both, NCOA1 or NCOA2. Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP. Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia.
Anti-AASDHPPT antibody produced in rabbit affinity isolated antibody
anti-AASDHPPT-antibody
Rabbit polyclonal anti-AASDHPPT antibody
Anti-AASDHPPT antibody
Anti-AASDHPPT antibody
Rabbit Polyclonal Anti-AASDHPPT Antibody（北京代理）
Rabbit polyclonal anti-AASDHPPT antibody
Anti-AASDHPPT antibody
Rabbit polyclonal anti-AASDHPPT antibody
Rabbit Polyclonal Anti-AASDHPPT Antibody
