P039 Polymyxin B2 sulfate, EvoPure/硫酸多粘菌素B2, EvoPure

Polymyxin B2 sulfate, EvoPure/硫酸多粘菌素B2, EvoPure
产品编号：P039 
产品规格：10mg

CAS Number	N/A
Molecular Formula	C55H96N16O13 · H2SO4
Molecular Weight	1287.52 g/mol
Form	Powder
Appearance	White powder
Purity Level	≥98.0%
Solubility	Water: Soluble
Source	Pseudomonas sp.
Storage Conditions	2-8 °C

Description
Polymyxin B2 sulfate is one of several polypeptide components that comprises the antibiotic polymyxin B sulfate. The unique fatty acid moiety found in polymyxin B2 is 6-methylheptanoic acid (6-MHA).
TOKU-E offers five forms of polymyxin B sulfate: polymyxin B sulfate (P007), polymyxin B1 sulfate, EvoPure? (P037),polymyxin B1-I sulfate, EvoPure? (P038), polymyxin B2 sulfate, EvoPure? (P039), and polymyxin B3 sulfate, EvoPure? (P040). EvoPure? products are purified single antibiotic fractions, most >99% pure. High purity EvoPure? polymyxin products can be used to analyze the specifc effects of individual polymyxin fractions.
Mechanism
Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram negative bacteria leading to lysing of the cell. Polymyxin B only needs to interact with LPS, it is not required to enter the cell.
Spectrum
Polymyxin B sulfate targets the outer membrane of gram negative bacteria especially Pseudomonas aeruginosa.
Microbiology Applications
Polymyxin B sulfate is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients. Representative MIC values include:Pseudomonas aeruginosa 0.25 μg/mL – 1 μg/mL
For a complete list of polymyxin B sulfate MIC values, click here.Plant Biology Applications