特别提示:包括重组人N-乙酰氨基葡糖-6-硫酸酯酶在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!
产品名称:重组人N-乙酰氨基葡糖-6-硫酸酯酶
英文名称:Recombinant Human N-Acetylglucosamine-6-Sulfatase
产品货号:JN0530
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Val37-Leu552在C端含有His标签。
N-Acetylglucosamine-6-Sulfatase质量控制:>95%(还原性SDS-PAGE)
N-Acetylglucosamine-6-Sulfatase制剂:液体
N-Acetylglucosamine-6-Sulfatase保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于N-Acetylglucosamine-6-Sulfatase:
N-Acetylglucosamine-6-Sulfatase is a member of the Sulfatase family. N-Acetylglucosamine-6-Sulfatase is required for the lysosomal degradation of the Glycosaminoglycans (GAG) Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase hydrolyzes the 6-Sulfate groups of the N-Acetyl-D-Glucosamine 6-Sulfate units of Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase binds 1 Calcium ion per subunit. N-Acetylglucosamine-6-Sulfatase deficiency are the cause of Mucopolysaccharidosis Type 3D (MPS3D), an inborn error leading to lysosomal accumulation of heparan sulfate. MPS3D has profound mental deterioration, hyperactivity, and relatively mild somatic manifestations.
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温馨提示:不可用于临床ZL。