Rabbit anti-INS Polyclonal Antibody,INS抗体

抗体描述：

产品名称：Rabbit anti-INS Polyclonal Antibody

产品别名：IDDM 2; IDDM2; ILPR; ins; INS_HUMAN; Insulin A chain; IRDN; MODY10; Proinsulin;

特异性：INS Antibody detects endogenous levels of total INS.

来源：Rabbit

反应种属：Human Mouse Rat

克隆性：Polyclonal

保存方法：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

产品描述：The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway (1). Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus (2).

用途范围： WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

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