Prostaglandin E2-1-glyceryl ester,2,3-dihydroxypropyl 7-[(2R)-3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]hept-5-enoate,37497-47-5

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产品名称：Prostaglandin E2-1-glyceryl ester

产品别名：2,3-dihydroxypropyl 7-[(2R)-3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]hept-5-enoate

CAS号：37497-47-5

英文别名：2,3-dihydroxypropyl 7-[(2R)-3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]hept-5-enoate

分子量：426.6

分子式：C₂₃H₃₈O₇

纯度：见爱必信官网

外观：A solution in ethanol

保存方法：Store at -80° C

描述：Prostaglandin E2-1-glyceryl ester is the glycero-ester of PGE2 , that has been shown to be synthesized by incubation of 2-Arachidonoyl glycerol (2-AG; sc-200794) with COX-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures. 2-AG has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. The biosynthesis of PGH, PGD, PGE, PGF, and TXA-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. Little is known about the biological activity of these 1-glyceryl prostaglandin derivatives.

应用：The glycero-ester of PGE2 showing similarity to natural endocannabinoids

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