Dantrolene, Sodium Salt,丹曲洛林钠盐水合物,14663-23-1

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试剂描述：

产品名称：Dantrolene, Sodium Salt

产品别名：1-[(5-­(p-Nitro­phenyl)­fur­furyl­idene)­amino]­hydan­toin sodium salt

CAS号：14663-23-1

英文别名：1-[(5-­(p-Nitro­phenyl)­fur­furyl­idene)­amino]­hydan­toin sodium salt

分子量：336.23

分子式：C₁₄H₉N₄O₅•Na

纯度：>95%

外观：见爱必信官网

保存方法：Store at room temperature

描述：Dantrolene is a small molecule inhibitor of the Ryanodine receptor and a calcium channel protein inhibitor (see Ryanodine, ). Blockade of Ca²⁺ release from the sarcoendoplasmic reticulum, strongly related to excitation and contraction of muscles, generates a muscle relaxant effect correlated with Dantrolene. The neurotoxicity presented by pronounced glutamate activity is correlated to excessive rises in cytoplasmic Ca²⁺ levels, and Dantrolene is accordingly indicated as a neuroprotective agent against neurotrasmitter-induced excitotoxicity. Dantrolene, Sodium Salt is an inhibitor of RyR-1 and RyR-3.

应用：A calcium channel protein inhibitor

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