FTY720 Phosphate,2-Amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl dihydrogen phosp hate,402615-91-2

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产品名称：FTY720 Phosphate

产品别名：2-​amino-​2[2-​(4-​octylphenyl)ethyl]-​1,​3-​propanediol,​ mono dihydrogen phosphate ester

CAS号：402615-91-2

英文别名：2-​amino-​2[2-​(4-​octylphenyl)ethyl]-​1,​3-​propanediol,​ mono dihydrogen phosphate ester

分子量：387.5

分子式：C₁₉H₃₄NO₅P

纯度：>98%

外观：见爱必信官网

保存方法：Store at -20° C

描述：FTY720 Phosphate is a derivative of ISP-1 (myriocin) that is a fungal metabolite of the Chinese herb Iscaria sinclarii and a structural analog of sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. It is phosphorylated by sphingosine kinase to the physiologically active phosphoric acid ester. FTY720 phosphate acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (EDG-1, EDG-3, EDG-4, and EDG-5), with IC₅₀ values of 0.2-6 nM.

应用：A derivative of ISP-1 that is a fungal metabolite as well as a structural analog of sphingosine

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