Tyrphostin AG 99,酪氨酸磷酸化YZ剂AG 99,118409-59-9

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试剂描述：

产品名称：Tyrphostin AG 99

产品别名：Tyrphostin A46; Tyrphostin 46; AG 99; (E)-2-Cyano-3-(3,4-dihydroxyphenyl)­-2-propenamide

CAS号：118409-59-9

英文别名：Tyrphostin A46; Tyrphostin 46; AG 99; (E)-2-Cyano-3-(3,4-dihydroxyphenyl)­-2-propenamide

分子量：204.18

分子式：C₁₀H₈N₂O₃

纯度：>98%

外观：见爱必信官网

保存方法：Store at -20° C

描述：Tyrphostin AG 99 is a potent, cell-permeable, reversible inhibitor of EGFR (epidermal growth factor receptor) and EGF-dependent cell proliferation. Stimulation of EGFRs result in tumor growth and proliferation, inhibition of apoptosis, stimulation of angiogenesis and the promotion of tissue invasion and metastasis. Tyrphostin AG 99 has been shown to inhibit EGFR phosphorylation and ERK1 and ERK2 activities.

应用：A potent, cell-permeable and reversible inhibitor of EGFR and EGF-dependent cell proliferation

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