N,N-Didesmethyl-O-desmethyl-(rac-Venlafaxine) Glucuronide,

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试剂描述：

产品名称：N,N-Didesmethyl-O-desmethyl-(rac-Venlafaxine) Glucuronide

产品别名：

CAS号：见爱必信官网

英文别名：

分子量：411.45

分子式：C₂₀H₂₉NO₈

纯度：见爱必信官网

外观：见爱必信官网

保存方法：Store at -20° C

描述：N,N-Didesmethyl-O-desmethyl-(rac-Venlafaxine) Glucuronide is a metabolite of Venlafaxine . Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake. In vitro studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.

应用：A metabolite of Venlafaxine

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