Phospho-AKT1(Thr308) Rabbit Polyclonal Antibody,AKT1(Thr308)磷酸化抗体

抗体描述：

产品名称：Phospho-AKT1(Thr308) Rabbit Polyclonal Antibody

产品别名：AKT 1; AKT; AKT1; AKT1_HUMAN; MGC99656; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha;

特异性：Phospho-AKT1(Thr308) Antibody detects endogenous levels of AKT1 only when phosphorylated at Threonine 308.

来源：Rabbit

反应种属：Human, Mouse, Rat

克隆性：Polyclonal

保存方法：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

产品描述：an AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus. Tumorigenic in a mouse lymphoma model and activated (by phospho-Akt staining) and/or overexpressed in a number of cancers including breast, prostate, lung, pancreatic, liver, ovarian and colorectal. Inhibitor: RX-0201. Substrates include tuberin, Bad, Forkhead transcription factors, caspase-9, and glycogen synthase kinase-3.

用途范围： WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

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