特别提示:包括重组人TARC/CCL17在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!
产品名称:重组人TARC/CCL17
英文名称:Recombinant Human Thymus and Activation Regulated Chemokine/CCL17
产品货号:GS4529
产品规格:5μg
分子量:Approximately 8.1kDa,a single non-glycosylated polypeptide chain containing 71 amino acids.
储存条件:冷冻(-20℃)
概述Human CCL17 also known as thymus and activation-related chemokine(TARC)is encoded by the CCL17 gene located on the chromosome 16 in humans.It is expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently.CCL17 signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes.It plays an important role in skin diseases such as atopic dermatitis,bullous pemphigoid and mycosis fungoides.CCL17 has approximately 24 – 29%amino acid sequence identity with RANTES,MIP-1α,MIP-1β,MCP-1,MCP-2,MCP-3 and I-309.
使用说明This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
纯度 | >97%by SDS-PAGE and HPLC analyses. |
来源 | Escherichia coli. |
生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10ng/ml. |
成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150mM NaCl. |
内毒素 | Less than 1 EU/μg of rHuTARC/CCL17 as determined by LAL method. |
复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
氨基酸序列 | ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S |
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温馨提示:不可用于临床ZL。