Mouse Il6st/Interleukin-6 receptor subunit beta ELISA Kit

产品类型：
ELISA kit
研究领域：

产品概述：
EK00255E is a ready-to-use microwell,strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (Interleukin-6 receptor subunit beta) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Interleukin-6 receptor subunit beta The ELISA analytical biochemical technique of the EK00255E kit is based on Interleukin-6 receptor subunit beta antibody-Interleukin-6 receptor subunit beta antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Interleukin-6 receptor subunit beta antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, Interleukin-6 receptor subunit beta Appropriate sample types may include undiluted human body
细胞定位：
Cell membrane Single-pass type I membrane protein
分析类型：
Sandwich
检测方法：
spectrophotometrical
反应性：
Mouse
检测范围："

0.156-10ng/mL
试剂盒组分：
Assay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.
基因名称：
Il6st
功能：
Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases (PubMed:1602143). That causes phosphorylation of IL6ST tyrosine residues which in turn activates STAT3 (PubMed:10661409). Mediates signals which regulate immune response, hematopoiesis, pain control and bone metabolism (PubMed:10661409, PubMed:26255596, PubMed:25057188, PubMed:8552649). Has a role in embryonic development (PubMed:10661409). Does not bind IL6 (By similarity). Essential for survival of motor and sensory neurons and for differentiation of astrocytes (PubMed:10377352). Required for expression of TRPA1 in nociceptive neurons (PubMed:25057188). Required for the maintenance of PTH1R expression in the osteoblast lineage and for the stimulation of PTH-induced osteoblast differentiation (PubMed:25228504). Required for normal trabecular bone mass and cortical bone composition (PubMed:24339143, PubMed:9348227, PubMed:26255596).
应用：
For research use only
联系方式：

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