Basigin / Emmprin / CD147 Antibody (clone 5D8)

分子量：
42200 Da
细胞定位：
Antigen Cellular Localization:Cell membrane; Single-pass type I membrane protein Melanosome. Note=Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250|UniProtKB:P18572, ECO:0000269|PubMed:17081065}
形式：
Liquid. In PBS containing 0.02% sodium azide.
参考文献：
Kasinrerk W.,et al.J. Immunol. 149:847-854(1992).Miyauchi T.,et al.J. Biochem. 110:770-774(1991).Biswas C.,et al.Cancer Res. 55:434-439(1995).Wakasugi H.,et al.Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.Decastro R.,et al.Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Basigin / Emmprin / CD147 antibody (clone 5D8).
功能：
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
总结：
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
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