分子量:
104859 Da
细胞定位:
Antigen Cellular Localization:Membrane; Single-pass type I membrane protein
形式:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:
Rey-Gallardo, A., et al. Glycobiology 20(9):1139-1146(2010)Geretti, E., et al. Mol. Cancer Res. 8(8):1063-1073(2010)Guo-ping, W., et al. Ann Plast Surg 65(1):80-84(2010)Nasarre, C., et al. Cell Adh Migr 3(4):383-389(2009)Fassold, A., et al. Arthritis Rheum. 60(10):2892-2901(2009)
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Neuropilin-2 antibody (C-term K813).
功能:
High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.
总结:
This gene encodes a member of the neuropilin family ofreceptor proteins. The encoded transmembrane protein binds toSEMA3C protein {sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3C} and SEMA3F protein {semadomain, immunoglobulin domain (Ig), short basic domain, secreted,(semaphorin) 3F}, and interacts with vascular endothelial growthfactor (VEGF). This protein may play a role in cardiovasculardevelopment, axon guidance, and tumorigenesis. Multiple transcriptvariants encoding distinct isoforms have been identified for thisgene.
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