GLI2 Antibody (internal region)

分子量：
167783 Da
细胞定位：
Antigen Cellular Localization:Nucleus {ECO:0000250|UniProtKB:Q0VGT2}. Cytoplasm {ECO:0000250|UniProtKB:Q0VGT2}. Note=In keratinocytes, it is sequestered in the cytoplasm by SUFU. In the absence of SUFU, it translocates to the nucleus {ECO:0000250|UniProtKB:Q0VGT2} Isoform 2: Nucleus
形式：
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
参考文献：
Gli2 and gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. Haycraft CJ, Banizs B, Aydin-Son Y, Zhang Q, Michaud EJ, Yoder BK. PLoS Genet. 2005 Oct;1(4):e53. Epub 2005 Oct 28. PMID: 16254602
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality GLI2 antibody (internal region).
功能：
Has a dual function as a transcriptional activator and a repressor of the hedgehog (Hh) pathway. May play a role during embryogenesis.
总结：
This antibody is expected to recognise all four reported isoforms (NP_084655.1, NP_084656.1, NP_084657.1 and NP_005261.1)
联系方式：

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