Vesicular Monoamine Transporter 2, C-Terminus Antibody

分子量：
57 KDa
细胞定位：

形式：
Prepared from sheep serum by affinity purification using a column to which the peptide immunogen was coupled.
参考文献：
Erickson JD, Schafer MKH, Bonner TI, Eiden LE, Weihe E (1996) Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter. Proc Natl Acad Sci USA 93:5166-5171.Giros B, El Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, Caron MG (1991) Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. J Pharmacol Exptl Ther 56:2139-2142.Haycock JW, Becker L, Ang, L, Furukawa Y, Hornykiewicz O, Kish SJ (2003) Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum. J Neurochem 87:574-585.Witkovsky P, Arango-Gonzalez B, Haycock JW, Kohler K (2004) Rat retinal dopaminergic neurons: Differential maturation of somatodendritic and axonal compartments. J Comp Neurol 481:352-362.
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Vesicular Monoamine Transporter 2, C-Terminus antibody.
功能：

总结：
Vesicular neurotransmitter transporters sequester the transmitters into synaptic vesicles (Erickson et al., 1996). The vesicular monoamine transporter 2 (VMAT2) is responsible for catecholamine and serotonin storage in central synapses. Antibodies specific for VMAT have been used to monitor expression of the transporter during development and in aging and can be effectively used as a marker for monoamine terminals (Haycock et al., 2003; Witkovsky et al., 2005).
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