特别提示:包括重组人酪氨酸蛋白激酶BLK在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!
产品名称:重组人酪氨酸蛋白激酶BLK
英文名称:Recombinant Human Tyrosine-Protein Kinase BLK
产品货号:JN1774
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Gly2-Pro505在C端含有His标签。
BLK质量控制:>95%(还原性SDS-PAGE)
BLK制剂:液体
BLK保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于BLK:
Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
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温馨提示:不可用于临床ZL。