产品货号:jlcR2022 英文名称 :HBeAg (2E9) 中文名称 :人乙型肝炎e抗原单克隆（包被）抗体 别 名 :Hepatitis B Virus E Antigen; HBe antigen; HBeAg; HBVgp4; Pre C,C; Precore protein; Precore/core; Precore/core ORF; Precore/core protei; HBEAG_HBVD3; External core antigen; HBeAg; p25. 研究领域 :免疫学 细菌及病毒 抗体来源 :Mouse 克隆类型 :Monoclonal 克 隆 号 :2E9 交叉反应 :Hepatitis B virus 产品应用 :ELISA=1:500-1000 IHC-F=1:400-800 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 :18kDa 性 状 :Lyophilized or Liquid 浓 度 :1mg/ml 免 疫 原 :HBeAg full length protein: 亚 型 :IgG 纯化方法 :affinity purified by Protein G 储 存 液 :0.01M TBS(pH7.4) with 0.03% Proclin300 保存条件 :Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed :PubMed 产品介绍 : Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.
Function: May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
Subunit: Homodimerizes.
Subcellular Location: Secreted. Host nucleus.
Post-translational modifications: Phosphorylated. Cleaved by host furin.
Similarity: Belongs to the orthohepadnavirus precore antigen family.
SWISS: Q89714
Gene ID: 944568
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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