特别提示:包括Atazanavir Sulfate在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!
产品名称:Atazanavir Sulfate
英文名称:Atazanavir Sulfate
产品货号:L10099
产品规格:5mg|10mg|50mg|250mg
属性
CAS号 | 229975-97-7 |
分子式 | C38H52N6O7.H2SO4 |
分子量 | 802.93 |
溶解性 | Soluble in water(4-5mg/ml),and methanol. |
存贮条件 | 储存温度2-8℃ |
描述
应用 | A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. |
产品介绍 | Atazanavir Sulfate是一种HIV protease(HIV蛋白酶)YZ剂,YZHIV Atazanavir,Ki值为2.66 nM。 |
备注 | Atazanavir is aHIV proteaseinhibitor withKiof 2.66 nM. |
生化机理 | Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.Has shown to be generally more potent than the five currently approved HIV-1 Prt inhibitors.Atazanavir(BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner,with a EC50 of approximately 47 nM.Also highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity.Atazanavir(BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations. |
别名 | BMS-232632-05;阿扎那韦硫酸盐;BMS-232632-05;Reyataz;BMS 232632 sulfate;BMS-232632 sulfate;BMS232632 sulfate;Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate sulfate |
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Atazanavir Sulfate(229975-97-7)(≥98%),BMS232632 sulfate,Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamat,BMS 232632 sulfate,BMS-232632-05,BMS-232632 sulfate,阿扎那韦硫酸盐,Reyataz质量上佳,价格普惠,欢迎广大新老客户踊跃订购。
温馨提示:不可用于临床ZL。