重组人Kallikrein-1(带His标签)

特别提示：包括重组人Kallikrein-1(带His标签)在内，本公司的所有产品仅可用于科研实验，严禁用于临床YL及其他非科研用途！

产品名称：重组人Kallikrein-1(带His标签)
英文名称：Recombinant Human Kallikrein-1, His
产品货号：GS4628
产品规格：20μg

分子量：Approximately 29.7kDa,a single non-glycosylated polypeptide chain containing 268 amino acids with 6×His at C-terminus.
储存条件：冷冻（-20℃）

概述

Kallikreins are members of the peptidase S1 family,which is a highly conserved serine proteases family.Fifteen kallikreins who seen coding genes are located in a cluster on chromosome 19.Human kallikrein1(KLK1),also known as tissue kallikrein,is functionally conserved in its capacity to cleave the low molecular weight kininogen to release the vasoactive peptide,Lys-bradykinin which plays a role in regulating vasodilation,blood pressure reduction,smooth muscle relaxation and contraction,pain induction and inflammation.Additionally,it have been reported,and growing evidence suggests that many kallikreins are implicated in carcinogens is and some have potential as novel cancer and other disease biomakers.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The specific activity determined by cleaving a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin(PFRAMC)is not less than 1,500 pmoles/min/μg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHuKLK-1,His as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MWFLVLCLAL SLGGTGAAPP IQSRIVGGWE CEQHSQPWQA ALYHFSTFQC GGILVHRQWV LTAAHCISDN YQLWLGRHNL FDDENTAQFV HVSESFPHPG FNMSLLENHT RQADEDYSHD LMLLRLTEPA DTITDAVKVV ELPTEEPEVG STCLASGWGS IEPENFSFPD DLQCVDLKIL PNDECKKAHV QKVTDFMLCV GHLEGGKDTC VGDSGGPLMC DGVLQGVTSW GY

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