重组人平足蛋白(Podoplanin)现货供应

特别提示：包括重组人平足蛋白(Podoplanin)在内，本公司的所有产品仅可用于科研实验，严禁用于临床YL及其他非科研用途！

产品名称：重组人平足蛋白(Podoplanin)
英文名称：Recombinant Human Podoplanin
产品货号：JN0610
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala23-Leu131在C端含有His标签。

Podoplanin质量控制：＞95%(还原性SDS-PAGE)

Podoplanin制剂：

Lyophilized

Podoplanin保存：

冻干蛋白应长期保存在-20℃以下，室温也可稳定保存3周时间
复溶后的蛋白溶液可在4℃保存2～7天。
建议根据使用量，将复溶后的蛋白溶液分装冻存在-20℃以下，可储存长达3个月。

Podoplanin复溶：

打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml.
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Podoplanin：

Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, and major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. It requires for normal lung cell proliferation and alveolus formation at birth and Induces platelet aggregation. Nevertheless, it doesn’t have any effect on amino acid transport and the aquaporin-type water channels.

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