内毒素:n/a
纯度:n/a
活性:n/a
产品背景:Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
产品描述:This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 30.2 kDa.
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http://www.acrobiosystems.cn/P1607-Biotinylated_Human_Siglec_15_%7C_CD33L3_Protein_HisAvitag_%28recommended_for_biopanning%29.html
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