Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His Tag

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>90% as determined by SDS-PAGE.

活性:
Measured by its binding ability in a functional ELISA. Immobilized Human BAFF, Fc Tag (Cat. No. BAF-H4268) at 5 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque BCMA, His Tag (Cat. No. BCA-C52H7) with a linear range of 0.078-0.625 μg/mL (QC tested).

产品背景:
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

产品描述:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.9 kDa. The protein migrates as 16-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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