品名 | anti- Cytokeratin 1-specific antibody |
货号 | FNab02211 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I. |
免疫原 | keratin 1 |
别称 | 67 kDa cytokeratin, CK 1, CK1, Cytokeratin 1, keratin 1, KRT1 |
分子量 | 67 kDa |
Uniprot ID | P04264 |
适用种属 | Human, Mouse |
验证应用 | ELISA, IP, IF, WB, IHC |
建议稀释比例 | WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
图片 | | Immunohistochemistry of paraffin-embedded human lung cancer using FNab02211(KRT1-specific antibody) at dilution of 1:50 |
| mouse skin tissue were subjected to SDS PAGE followed by western blot with FNab02211(KRT1-specific Antibody) at dilution of 1:1000 |
注意事项 | Cytokeratin 1-specific antibody|Cytokeratin 1-specific抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab02211/ |