Cytokeratin 1-specific抗体| Cytokeratin 1-specific antibody

货号  PAab02211

蛋白别名  67 kDa cytokeratin antibody, CK 1 antibody, CK1 antibody, Cytokeratin 1 antibody, keratin 1 antibody, KRT1

蛋白介绍

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I.

产品描述

建议稀释比例

WB:1:500-1:5000;IP:1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200

IHC

Immunohistochemistry of paraffin-embedded human lung cancer using PAab02211(KRT1-specific antibody) at dilution of 1:50

Western blot

mouse skin tissue were subjected to SDS PAGE followed by western blot with PAab02211( KRT1-specific Antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!)

武汉维克赛思科技有限公司

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