特别提示:包括重组人PROC(蛋白酶K依赖性蛋白C)在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!
产品名称:重组人PROC(蛋白酶K依赖性蛋白C)
英文名称:Recombinant Human Vitamin K-Dependent Protein C/Blood Coagulation Factor XIV
产品货号:JN0837
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Thr19-Pro461在C端含有His标签。
PROC质量控制:>95%(还原性SDS-PAGE)
PROC制剂:液体
PROC保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PROC:
Vitamin K-Dependent Protein C (PROC) is a serine protease that belongs to the peptidase S1 family. Human PROC is synthesized as a single chain precursor, which is cleaved into a light chain and a heavy chain held together by a disulfide bond. PROC is expressed in plasma and liver. PROC contains one peptidase S1 domain, one Gla (γ-carboxy-glutamate) domain and two EGF-like domains. PROC is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Defects in PROC are the cause of thrombophilia due to protein C deficiency, autosomal dominant (THPH3) and autosomal recessive (THPH4).
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温馨提示:不可用于临床ZL。