Reactant for preparation of: .Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP .Cytotoxic and antimitotic agents .Insulin-like growth factor 1 receptor inhibitors .Antitumoral agents .Factor Xa inhibitor .Potential antivascular agents .Gli1-mediated transcription in the Hedgehog pathway .Inhibitors of receptor tyrosine kinase with antiangiogenic effects .PKCθ inhibitors .HIV protease inhibitors