Purified Anti-Mouse CD279/PD-1 Monoclonal Antibody[29F.1A12]_详细资料

产品信息

货号： E-AB-F1131A 抗体英文名： Purified Anti-Mouse CD279/PD-1 Monoclonal Antibody[29F.1A12] 浓度： 0.5 mg/mL 应用范围： FCM, WB, IHC, IF 宿主： Rat 供应商：武汉伊莱瑞特生物科技股份有限公司数量：现货适应物种： Mouse 标记物： Unconjugated 克隆性：单克隆亚型： Rat IgG2a, κ 免疫原： 0 规格： 50 μg/ 100 μg

产品货号：E-AB-F1131A
产品类别：流式抗体-抗小鼠（Anti-Mouse)流式抗体
产品名称：纯抗抗小鼠 CD279/PD-1 流式抗体
Purified Anti-Mouse CD279/PD-1 Monoclonal Antibody
Antigen Information：

Alternate Names PD-1, Programmed Death-1

Uniprot ID Q02242

Background CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Product Details：

Form Liquid

Clone No. 29F.1A12

Host Rat

Isotype Rat IgG2a

Reactivity Mouse

Application FCM,IHC

Storage Buffer PBS with 0.05% Proclin300

Shipping Biological ice pack at 4 ℃

Stability & Storage Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.

Recommended Use：
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 10<sup>6</sup> cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Related Protocols：
流式细胞表面染色步骤
流式细胞术样本制备技术

Troubleshooting：
流式实验常见问题及解决方案

References：
1. Nishimura H, et al. 2001. Science 291:319
2. Agata Y, et al. 1996. Int. Immunol. 8:765
3. Liang SC, et al. 2003. Eur. J. Immunol. 33:2706
4. Barber DL, et al. 2006. Nature 439:682
5. Keir ME, et al. 2005. J. Immunol. 175:7372
6. Koehn BH. et al. 2008.

点击查看流式抗体（flow cytometry antibody）列表
更多详情请参见Elabscience官方网站

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Alternate Names	PD-1, Programmed Death-1
Uniprot ID	Q02242
Background	CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Form	Liquid
Clone No.	29F.1A12
Host	Rat
Isotype	Rat IgG2a
Reactivity	Mouse
Application	FCM,IHC
Storage Buffer	PBS with 0.05% Proclin300
Shipping	Biological ice pack at 4 ℃
Stability & Storage	Keep as concentrated solution. Store at 2~8℃. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.