SP1 多克隆抗体_详细资料

产品信息

抗体英文名： SP1 Polyclonal Antibody 浓度： 1mg/mL 应用范围： WB,IHC-p,IF,ELISA 宿主： Rabbit 供应商：武汉伊莱瑞特生物科技股份有限公司数量：现货适应物种： Human,Mouse,Rat 标记物： Unconjugated 克隆性：单克隆亚型： IgG 免疫原： Synthesized peptide derived from human Sp1 around the non-phosphorylation site of Thr739. 规格： 20μL/ 60μL/ 120μL/ 200μL

Overview

Synonyms SP1, TSFP1, Transcription factor Sp1

Swissprot P08047

Gene ID 6667

Source Rabbit

Reactivity Human,Mouse,Rat

Immunogen Synthesized peptide derived from human Sp1 around the non-phosphorylation site of Thr739.

Application WB,IHC-p,IF,ELISA

Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Concentration 1mg/mL

Clonality Polyclonal

Research Areas Stem cells,Cancer,Epigenetics

Properties

Isotype IgG

Purification Affinity purification

Conjugation Unconjugated

Calculated MV 81kDa

Observed MV 85kDa

Storage instructions Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Background
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.

Image

Western Blot analysis of various cells with Sp1 Polyclonal Antibody.

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SP1 多克隆抗体

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Synonyms	SP1, TSFP1, Transcription factor Sp1
Swissprot	P08047
Gene ID	6667
Source	Rabbit
Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from human Sp1 around the non-phosphorylation site of Thr739.
Application	WB,IHC-p,IF,ELISA
Recommended dilution	WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Concentration	1mg/mL
Clonality	Polyclonal
Research Areas	Stem cells,Cancer,Epigenetics

Isotype	IgG
Purification	Affinity purification
Conjugation	Unconjugated
Calculated MV	81kDa
Observed MV	85kDa
Storage instructions	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background	Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.