重组人心室肌球蛋白轻链LC1

产品英文名称：
Recombinant Human MutS Homolog 6

英文简称:
MSH6

中文名称:
重组人MutS同系物6

背景资料:
MSH6 deficiency result in hereditary non-polyposis colorectal cancer （Lynch syndrome）. HNPCC is an autosomal， dominantly inherited disease linked with rise in cancer susceptibility. MSH6 is is known by its familial predisposition to premature onset colorectal carcinoma （crc） and extra-colonic cancers of the gastrointestinal， urological and female reproductive tracts.MSH6 is involved in repairing DNA. MSH6 protein repairs mistakes that occure during DNA replication in preparation for cell division. The MSH6 protein bonds with MSH2 protein and form an active protein complex which recognizes specific parts on the DNA where mistakes have bMSH6 Human Recombinant produced in E.Coli is single， a non-glycosylated， Polypeptide chain containing 51 amino acids （350-400 a.a.） having a total Mw of 33 kDa. Human MSH6 is fused to a GST tag and purified by proprietary chromatographic techniques.n made during DNA replication. MLH1-PMS2 protein complex， afterwards takes over with the repair. MSH6 gene is part of the set of the mismatch repair （MMR） genes.

产品描述:
MSH6 Human Recombinant produced in E.Coli is single， a non-glycosylated， Polypeptide chain containing 51 amino acids （350-400 a.a.） having a total Mw of 33 kDa. Human MSH6 is fused to a GST tag and purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:


溶解建议:
Sterile Filtered clear solution. MSH6 is supplied in 50mM Tris-Acetate， pH-7.5， 1mM EDTA and 20% Glycerol.

保存建议：
Store at 4℃ if entire vial will be used within 2-4 weeks.Store， frozen at -20℃ for longer periods of time.Please avoid freeze thaw cycles.
其他简介：

  ProSpec是一家细胞因子蛋白及相关抗体生产和研发品Pai。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种Z多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。