百欧博伟生物ATCC 2091白色念珠菌 ATCC菌种

白色念珠菌（Monilia albican 或 canidia Albicans），是一种真菌，通常存在于正常人口腔，上呼吸道，肠道及阴道，一般在正常机体中数量少，不引起疾病，当机体免疫功能或一般防御力下降或正常菌群相互制约作用失调，则本菌大量繁殖并改变生长形式（芽生菌丝相）侵入细胞引起疾病。
Candida albicans 菌株拉丁名

(Robin) Berkhout

(ATCC® 2091™) ATCC菌种 编号

Permits and Restrictions View Permits

Deposited As Endomyces albicans (Robin) Vuillemin

Strain Designations 菌株别名 132 [CBS 2730, CIP 1180.79, IFO 1393, NCYC 854]

Application Pharmaceutical and Personal Care

Biosafety Level 生物安全等级 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format 提供形式 freeze-dried

Storage Conditions Frozen 保藏方法 : -80℃ or colder

Freeze-Dried 冻干物 : 2℃ to 8℃

Live Culture 活菌 : See Propagation Section

Type Strain 模式菌株 no

Antigenic Properties Serotype A Ref

Preceptrol® no

Morphology Colonies after 3 days cream-colored, dull, often becoming wrinkled with a mycelial border on prolonged incubation.

Yeast cells globose to short-ovoid, hyaline, 2-7 x 3-8.5 µm, single or budding, occasionally forming short chains.

Medium  培养基 ATCC® Medium 28: Emmons' modification of Sabouraud's agar

ATCC® Medium 200: YM agar or YM broth

ATCC® Medium 1245: YEPD

Growth Conditions 生长条件

Temperature 培养温度 : 28℃

Atmosphere 需氧情况 : Typical aerobic

Name of Depositor R Chodat

Cross References Nucleotide (GenBank) : KU729048 ITS including 5.8S rRNA gene

References 参考文献 Morrison CJ, et al.

Heterogeneity of the purified extracellular aspartyl proteinase from Candida albicans:

characterization with monoclonal antibodies and N-terminal amino acid sequence analysis. Infect. Immun. 61: 2030-2036, 1993. PubMed: 8478090

British Pharmacopoeia Commission Test for sterility. London, UK:British Pharmacopoeia Commission;

British Pharmacopoeia Appendix XVI A, 2003 British Pharmacopoeia Commission Tests for microbial contamination.

London, UK:British Pharmacopoeia Commission;British Pharmacopoeia Appendix XVI B, 2003

Wagner T, et al. pH-dependent denaturation of extracellular aspartic proteinases from Candida species. J. Med. Vet. Mycol. 33: 275-278, 1995. PubMed: 8531028

Morrison CJ, et al. Purification and characterization of the extracellular aspartyl proteinase of Candida albicans: removal of extraneous proteins and cell wall mannoprotein and evidence for lack of glycosylation. J. Gen. Microbiol. 139: 1177-1186, 1993. PubMed: 8360611

European Pharmacopoeia Commission Sterility. Strasbourg, France:European Pharmacopoeia Commission;European Pharmacopoeia EP 2.6.1, 1997

European Pharmacopoeia Commission Microbial contamination of products not required to comply with the test for sterility (total viable aerobic count).

Strasbourg, France:European Pharmacopoeia Commission;European Pharmacopoeia EP 2.6.12, 1997

Microbial limit test. Tokyo, Japan:Japanese Pharmacopoeia;JP Jp14e.part I.35. Microbial limit test for crude drugs. Tokyo, Japan:Japanese Pharmacopoeia;JP JP14e.part I.36.

U.S. Pharmacopeia General Chapters: <1072> Disinfectants and Antiseptics. Rockville, MD. USP34-NF29, 2011 ISO/CD 11133:2009,

Annex E. Test microorganisms for commonly used culture media (giving information on the culture medium, culture conditions, test microorganisms, culture collection number of test organisms and the expected reactions) Corry, JEL, Curtis, GDW and Baird, RM (Eds) Handbook of Culture Media for Food and Water Microbiology.

Royal Society of Chemistry, In preparation. ICFMH-WPCM. Wagner T, et al. pH-dependent denaturation of extracellular aspartic proteinases from Candida species. J. Med. Vet. Mycol. 33: 275-278, 1995. PubMed: 8531028