Anti–beta Amyloid Rabbit pAb_详细资料

产品信息

货号： GB11307 克隆性：多克隆

Product Information

Description
beta Amyloid rabbit polyclonal

Protein full name Amyloid beta A4 protein

Synonyms
APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, amyloid beta precursor protein, preA4

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse APP

Isotype IgG

Purity Affinity purification

Subcellular location
Membrane

Uniprot ID
P12023,P08592

Applications

Applications
IHC,IF

Species
Mouse,Rat

Dilution
1:500-1:1000

Positive tissue
brain

Background
Functions as a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis.

Images

Immunohistochemistry analysis of paraffin-embedded Rat brain using APP(GB11307) at dilution of 1:500

Immunohistochemistry analysis of paraffin-embedded mouse brain using APP(GB11307) at dilution of 1:500

Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.

Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE: This product is intended for research only.

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Description	beta Amyloid rabbit polyclonal
Protein full name	Amyloid beta A4 protein
Synonyms	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, amyloid beta precursor protein, preA4
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse APP
Isotype	IgG
Purity	Affinity purification
Subcellular location	Membrane
Uniprot ID	P12023,P08592

Applications	IHC,IF
Species	Mouse,Rat
Dilution	1:500-1:1000
Positive tissue	brain

	Immunohistochemistry analysis of paraffin-embedded Rat brain using APP(GB11307) at dilution of 1:500

	Immunohistochemistry analysis of paraffin-embedded mouse brain using APP(GB11307) at dilution of 1:500

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.