CD3-PerCP-Vio700/CD3 antibodies, mouse

品Pai:miltenyi，产品名称：CD3-PerCP-Vio700, mouse
CD3 antibodies, mouse - Miltenyi Biotec
货号：130-109-841
Clone REA641 recognizes the mouse CD3 complex, which is expressed on all mature T lymphocytes, NKT cells and during the development of thymocytes. CD3, also known as T3, belongs to the Ig superfamily. It consists of CD3ε, δ, γ and ζ chains and forms a TCR complex by associating with TCR α/β or γ/δ chains. The TCR does not possess intracellular signaling domains, uncoupling Ag recognition from T cell signaling. The TCR is instead noncovalently associated with a multisubunit signaling apparatus, consisting of the CD3εγ and CD3εδ heterodimers and the CD3ζζ homodimer, which collectively form the TCR-CD3 complex. CD3 is involved in T cell activation, signal transduction, and antigen recognition by binding the peptide/MHC antigen complex.
Additional information: Clone REA641 displays negligible binding to Fc receptors.

Alternative namesT cell antigen receptor complex, T3, AI504783, CD3epsilon, T3E, Ctg-3, Ctg3, T3g

Clone and isotype

Clone	Isotype
REA641	recombinant human IgG1