CD197 (CCR7)-Biotin/CD197 (CCR7) antibodies, mouse

品Pai:miltenyi，产品名称：CD197 (CCR7)-Biotin, mouse 200 tests
CD197 (CCR7) antibodies, mouse - Miltenyi Biotec
货号：130-101-987
Clone 4B12 reacts with CD197 (CCR7), a chemokine receptor for chemokines CCL19 and CCL21. CD197, like other chemokine receptors has seven-transmembrane spanning domains and signals via G proteins. Expression of CD197 is found on semi-mature and mature dendritic cells (DCs), naïve B and T cells, regulatory T (Treg) cells, a subpopulation of T cells called central memory T cells and non-immune malignant cells. CD197 is involved in regulating homing of immune cells, immunity to pathogens, immune tolerance, development and function of Tregs and manifestation of autoimmunity.

Alternative namesCCR7, CC-CKR-7, CCR-7, Cdw197, CMKBR7, EBI1, Ebi1h

Clone and isotype

Clone	Isotype
4B12	rat IgG2aκ