CD197 (CCR7) pure/CD197 (CCR7) antibodies, human

品Pai:miltenyi，产品名称：CD197 (CCR7) pure, human
CD197 (CCR7) antibodies, human - Miltenyi Biotec
货号：130-093-626
CCR7 is a chemokine receptor with a C-C motif that mediates homing of T cells to secondary lymphoid organs via high endothelial venules (HEV). For example, naive T cells migrate very efficiently through lymph nodes using the adhesion molecules L-selectin, CD62L, and CCR7. Ligands for CCR7, e.g. CCL19, are expressed by the HEV of secondary lymphoid organs, by parenchymal cells within T cell zones of lymph nodes, and by endothelial cells at the openings of lymphatic vessels within peripheral tissues. Expression of CCR7 and the CD45RA isoform distinguishes three subsets of T cells: naive T cells (CCR7⁺CD45RA⁺), central memory T cells (CCR7⁺ CD45RA^–), and effector memory T cells (CCR7^– CD45RA^–).

Alternative namesCCR7, BLR-2, CC-CKR-7, CCR-7, Cdw197, CMKBR7, EBI-1

Clone and isotype

Clone	Isotype
FR 11-11E8	mouse IgG1κ