FITC标记的DNA聚合酶μ/DNA pol μ抗体_详细资料

产品信息

货号： LM-13021R-FITC 保存条件： -20 °C 浓度： 1mg/ml 应用范围： ICC=1:50-200 IF=1:50-200 形态：粉末、液体、冻干粉亚型： IGg 免疫原：详见说明书适应物种： Human, Mouse, Rat, Horse, 宿主： Human, Mouse, Rat, Horse, 标记物： FITC标记抗体名： Anti-DNA polymerase mu/FITC 抗体英文名： Anti-DNA polymerase mu/FITC 保质期： 1年抗原来源： Rabbit 克隆性：多克隆目录编号： LM-13021R-FITC 级别： 1 靶点：详见说明书数量：大量供应商：上海联迈生物工程有限公司规格： 100ul

FITC标记的DNA聚合酶μ/DNA pol μ抗体

英文名称 Anti-DNA polymerase mu/FITC

中文名称 FITC标记的DNA聚合酶μ/DNA pol μ抗体

别    名 DNA Polymerase Mu; DNA-directed DNA polymerase mu; DNA-directed DNA/RNA polymerase mu; DPOLM_HUMAN; FLJ35482; Pol iota; Pol Mu; Polm; POLM protein; Polymerase (DNA directed) mu; Polymerase DNA directed mu; Tdt N; Tdt-N; TdtN; Terminal transferase.

规格价格 100ul/2980元购买        大包装/询价

说明书 100ul

研究领域细胞生物  表观遗传学

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Horse,

产品应用 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 55kDa

性    状 Lyophilized or Liquid

浓    度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human DNA polymerase mu

亚    型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品介绍 background:
DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.

Function:
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in a number of tissues. Abundant in thymus.

Similarity:
Belongs to the DNA polymerase type-X family.
Contains 1 BRCT domain.

Database links:
UniProtKB/Swiss-Prot: Q9NP87.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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FITC标记的DNA聚合酶μ/DNA pol μ抗体

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英文名称	Anti-DNA polymerase mu/FITC
中文名称	FITC标记的DNA聚合酶μ/DNA pol μ抗体
别名	DNA Polymerase Mu; DNA-directed DNA polymerase mu; DNA-directed DNA/RNA polymerase mu; DPOLM_HUMAN; FLJ35482; Pol iota; Pol Mu; Polm; POLM protein; Polymerase (DNA directed) mu; Polymerase DNA directed mu; Tdt N; Tdt-N; TdtN; Terminal transferase.
规格价格	100ul/2980元购买大包装/询价
说明书	100ul
研究领域	细胞生物表观遗传学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Horse,
产品应用	ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	55kDa
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human DNA polymerase mu
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair. Function: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. Subcellular Location: Nucleus. Tissue Specificity: Expressed in a number of tissues. Abundant in thymus. Similarity: Belongs to the DNA polymerase type-X family. Contains 1 BRCT domain. Database links: UniProtKB/Swiss-Prot: Q9NP87.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.