供应商:
安诺伦(北京)生物科技有限公司
保存条件:
Store product at –224oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
规格:
5 ug
研究领域:Apoptosis/Autophagy, Cancer, Cell Cycle, Cytoplasmic Tyrosine Kinases,
靶点/蛋白质:Recombinant human fusion protein NPM1 (1-117)-ALK (F1174L) (1058-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
来源:Sf9 insect cells using baculovirus
存储溶液:50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
参考文献:1. Benharroch, D.et.al: ALK-positive lymphoma: a single disease with a broad spectrum of morphology. Blood 91: 2076-2084, 1998. 2. Zhang, Q. et.al: STAT is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression.
特异性:Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
别名:NPM1: B23; NPMALK: ALK (Ki-1), CD246, NBLST3, TFG/ALK
应用:Kinase Assay
官网链接:https://www.signalchem.com/product_details.php?id=10614
商品关键词:NPM1-ALK Mutant (F1174L), Active,A19-19EG-05,SignalChem
简单描述:Recombinant human fusion protein NPM1 (1-117)-ALK (F1174L) (1058-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Species: Human
Tag: GST tag
Sequence: 1-117 (NPM1) 1058-end (F1174L) (ALK)
Genbank Number: U04946
Molecular Weight: ~108 kDa
官网链接: www.annoron.com
办公电话: 010-56256916
官方售后: 400-965-8633
企业QQ: 3198592576、3212874516
温馨提示:不可用于临床ZL。