供应商:
安诺伦(北京)生物科技有限公司
保存条件:
Store product at –367oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
研究领域:Cancer,
靶点/蛋白质:Recombinant human fusion protein TPM3 (1-258)-ROS1 (1881-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
来源:Sf9 insect cells using baculovirus
存储溶液:50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
参考文献:1. Lawlor, M W. et al: Mutations of tropomyosin 3 (TPM3) are common and associated with type 1 myofiber hypotrophy in ongenital fiber type disproportion. Hum Mutat. 2010 Feb;31(2):176-83. 2. Zhao C. et al: Detecting ALK, ROS1 and RET Fusion Genes in Cell Block Samples. Transl Oncol. 2014 Jun 17;7 (3):363-7.
特异性:Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
别名:TPM3: CAPM1; CFTD; hscp30; NEM1; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TM5; TPMsk3; TRKROS1: c-ros-1; MCF3; ROS
应用:Kinase Assay
官网链接:https://www.signalchem.com/product_details.php?id=10922
商品关键词:TPM3-ROS1 Mutant, Active,R14-19CG-BULK,SignalChem
简单描述:Recombinant human fusion protein TPM3 (1-258)-ROS1 (1881-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Species: Human
Tag: GST tag
Sequence: 1-258 (TPM3) - 1881-end (ROS1)
Genbank Number: NM_152263
Molecular Weight: 108 kDa
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温馨提示:不可用于临床ZL。