重组小鼠TNFRSF1B 重组蛋白

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、YL及其他非科研用途。

北京百奥莱博专业生产销*(代"售")重组小鼠TNFRSF1B 重组蛋白，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组小鼠TNFRSF1B 重组蛋白
编号：JN0472
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse Tumor Necrosis Factor Receptor II
品Pai：百奥莱博
产地：北京
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Val23-Gly258在C端含有His标签。

TNFRSF1B质量控制：＞95%(还原性SDS-PAGE)

TNFRSF1B制剂：冻干品

TNFRSF1B保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFRSF1B复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFRSF1B：
Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains: Tumor necrosis factor receptor superfamily member 1b and membrane form and Tumor necrosis factor-binding protein 2. TNFRSF1B is a receptor with high affinity for TNFSF2/TNF-α and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-α. TNFRSF1B mediates most of the metabolic effects of TNF-α. TNF-α-induced apoptosis suggests that it regulates TNF-α function by antagonizing its biological activity.

关于重组小鼠TNFRSF1B 重组蛋白的更详细说明，请致电我公司咨询，我们将以Z饱满的热情为您提供解答，此外，我公司专业供应下列产品：
BTN101207 1M Tris-HCl(pH8.5)(DNA级)
KFS098 SDS(10%)
SY0325 全能核酸酶 Benzonase Nuclease
YT413 溶菌酶(>20KU/mg) Lysozyme
BTN130540 二*异香豆素溶液(10mg/mL) Dichloroisocoumarin Solution
HR0131 植物核蛋白/细胞器蛋白提取试剂盒 Plant nuclear protein/organelle Protein Extraction Kit
YT917 TLR4激活剂(超纯LPS) Ultrapure LPS
YT060 高灵敏ECL化学发光试剂盒 High sensitive ECL chemiluminescence  kit
BTN80203 PAGE胶miRNA柱式回收试剂盒 miRNA column recovery kit for PAGE gel
SV1477 表达 lq E. coli 感受态细胞 ( GX级 )
SV0168 BsaWI限制性内切酶 BsaWI Restriction Endonuclease
KFS340 微核分析/遗传毒性分析荧光染料
SY0587 糖原PAS染色试剂盒 Glycogen (PAS) Stain kit
SV0740 StyI限制性内切酶 StyI Restriction Endonuclease
BTN130642 核酸内切酶VIII Endonuclease VIII
HR0954 细胞膜流动性(fluidity)TMA-DPH荧光检测试剂盒 Cell membrane fluidity (fluidity) TMA-DPH fluorescence detection kit
重组小鼠TNFRSF1B 重组蛋白关键词：重组TNFRSF1B,JN0472,Recombinant Mouse Tumor Necrosis Factor Receptor I,百奥莱博,重组小鼠TNFRSF1B蛋白


·重组人BH3结构域凋亡诱导蛋白(BID)
编号：JN1912
英文名称：Recombinant Human BH3-Interacting Domain Death Agonist
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Asp195表达纯化得来。

BID/BH3-interacting domain death agonist质量控制：＞95%(还原性SDS-PAGE)

BID/BH3-interacting domain death agonist制剂：液体

BID/BH3-interacting domain death agonist保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于BID/BH3-interacting domain death agonist：
BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.


重组小鼠TNFRSF1B 重组蛋白关键词：重组TNFRSF1B,JN0472,Recombinant Mouse Tumor Necrosis Factor Receptor I,百奥莱博,重组小鼠TNFRSF1B蛋白


·重组人磷酸甘露糖变位酶2(PMM2)
编号：JN2020
英文名称：Recombinant Human Phosphomannomutase 2
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ser246在C端含有His标签。

PMM2质量控制：＞95%(还原性SDS-PAGE)

PMM2制剂：液体

PMM2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于PMM2：
Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily. PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.

我公司正在优惠促销重组蛋白等系列产品，期待您的咨询选购重组小鼠TNFRSF1B 重组蛋白。