特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)哪里买,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)哪里买
编号:JN0841
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9
品Pai:百奥莱博
产地:北京
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln31-Gln152&Ser153-Gln692在C端含有His标签。
PCSK9质量控制:>95%(还原性SDS-PAGE)
PCSK9制剂:液体
PCSK9保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PCSK9:
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.
想要了解更多关于重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)哪里买的价格、品Pai、厂家、说明书、促销信息,请和我们联*(代"系")。此外我公司还销*(代"售")下面的产品:
·重组人ULBP-1
编号:JN1437
英文名称:Recombinant Human UL16 Binding Protein-1/NKG2D ligand 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gly26-Pro215在C端含有His标签。
ULBP-1质量控制:>95%(还原性SDS-PAGE)
ULBP-1制剂:冻干品
ULBP-1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
ULBP-1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于ULBP-1:
ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocomp*(代"a")tibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signaling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumor cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.
重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)哪里买关键词:C端His标签,重组人前蛋白转化酶枯草杆菌蛋白酶kexin-9,重组人PCSK9蛋白,JN0841
·重组人磷酸甲羟戊酸激酶(PMVK)
编号:JN2018
英文名称:Recombinant Human Phosphomevalonate Kinase
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Leu192在N端含有His标签。
PMVK质量控制:>95%(还原性SDS-PAGE)
PMVK制剂:液体
PMVK保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PMVK:
Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney; it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)哪里买关键词:C端His标签,重组人前蛋白转化酶枯草杆菌蛋白酶kexin-9,重组人PCSK9蛋白,JN0841
KFS120 伊红染液
YT038 Western及IP细胞裂解液 Cell lysis buffer for Western and IP
SV1002 标准 Taq 反应缓冲液
BTN130976 Oligo(dT)再生溶液 Oligo(dT) Recharger
WE0174 新型植物基因组DNA提取试剂盒 NewPurify Plant Genomic DNA Extraction Kit
YT391 dNTP混合溶液(25mM) dNTP Mixture (25mM each)
SV1652 pCMV-CLuc 2 对照质粒
BTN130923 LAMP扩增阳性对照 LAMP Positive Control
BTN131278 戊二醛磷酸缓冲固定液 Glutaraldehyde Fixative Solution
SY0101 SMAD-Luc荧光素酶报告基因质粒 SMAD luciferase reporter plasmid
HR0374 1M Tris (pH6.8) Tris 1M (pH6.8)
BTN140621 基因转染增强剂 Hexadimethrine bromide
SV0387 HaeIII限制性内切酶 HaeIII Restriction Endonuclease
SY0462 多聚L-赖*酸溶液(5mg/ml)(分子量15万~30万) Poly-L-lysine (5mg/ml), Mw 150,000-300,000
KFS223 Caspase-2蛋白检测试剂盒 Caspase-2 Detection Assay(Western Blot)
YT138 Caspase 1 活性检测试剂盒 Caspase 1 Activity Assay Kit
SV1279 Quick-Load 100 bp DNA Ladder
我公司正在优惠促销重组蛋白等系列产品,期待您的咨询选购重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)哪里买。
温馨提示:不可用于临床ZL。