特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
重组人CTLA-4(CD152)(细胞毒性T淋巴细胞相关抗原4) 重组蛋白的品Pai:百奥莱博,是优质的重组蛋白产品,用于生化研究,本产品质量好,且极具价格优势,深为用户称道,了解更多重组人CTLA-4(CD152)(细胞毒性T淋巴细胞相关抗原4)等重组蛋白产品请联*(代"系")我司咨询订购。
名称:重组人CTLA-4(CD152)(细胞毒性T淋巴细胞相关抗原4) 重组蛋白
编号:JN1240
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human Cytotoxic T-lymphocyte protein 4
品Pai:百奥莱博
产地:北京
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Lys36-Asp161在C端带有Fc标签。
CTLA-4/CD152质量控制:>95%(还原性SDS-PAGE)
CTLA-4/CD152制剂:冻干品
CTLA-4/CD152保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
CTLA-4/CD152复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于CTLA-4/CD152:
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence, a 126 aa extracellular domain (ECD) with one Ig-like V-type domain, a 21 aa transmembrane (TM) sequence, and a 41 aa cytoplasmic sequence.It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
欲了解更多重组人CTLA-4(CD152)(细胞毒性T淋巴细胞相关抗原4) 重组蛋白的品Pai、产地、价格及说明书等产品信息,请致电北京百奥莱博科技有限公司,我们将竭诚为您服务,另外,以下产品正在火爆促销:
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重组人CTLA-4(CD152)(细胞毒性T淋巴细胞相关抗原4) 重组蛋白关键词:重组人细胞毒性T淋巴细胞相关抗原4,重组人CTLA-4,重组人CTLA-4蛋白,重组人CD152,JN1240
·重组人B/T淋巴细胞衰减因子(BTLA)
编号:JN0629
英文名称:Recombinant Human B- and T-Lymphocyte Attenuator
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Lys31-Leu150在C端含有His标签。
BTLA质量控制:>95%(还原性SDS-PAGE)
BTLA制剂:冻干品
BTLA保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
BTLA复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于BTLA:
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses.
重组人CTLA-4(CD152)(细胞毒性T淋巴细胞相关抗原4) 重组蛋白关键词:重组人细胞毒性T淋巴细胞相关抗原4,重组人CTLA-4,重组人CTLA-4蛋白,重组人CD152,JN1240
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